Medicinal Chemistry and Drug Discovery
...we have been involved in rational drug design programs aimed at the discovery of promising candidates for the treatment of giardiasis and other important... Medicinal...

Dynamic Stereochemistry
The development of mechanistic insights into isomerization reactions and information about the conformational and configurational stability of chiral compounds...

Template-Directed Chemistry and Supramolecular Architectures
Supramolecular self-assembly has become a widely recognized tool for the formation of well-defined noncovalent...

 

 

Asymmetric Catalysis
Many biologically active compounds are chiral, and more than 50 % of today's top selling drugs are marketed as single enantiomers. The high and ever-increasing demand...

Stereoselective Sensing of Chiral Compounds
The ever-increasing demand for new biologically active chiral compounds, in particular pharmaceuticals and agrochemicals, continues to nurture...

Transition Metal Catalysis and Cross-Coupling Reactions
Palladium-catalyzed cross-coupling of aryl halides and boronic acids (Suzuki coupling), organostannanes (Stille), organosiloxanes (Hiyama), organozinc...

 

Kekeli Ekoue-KoviPeng ZhangKeith BentleyYang LiuBurcin Irfanoglu

Mol1

C. Wolf, Dynamic Stereochemistry of Chiral Compounds,
RSC Publishing, London, 2008

 


We thank NSF, NIH and ACS-PRF for financial support.